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“The only thing necessary for these diseases to the triumph is for good people and governments to do nothing.”


 

Caution: That Dose May Be Too High

By ABIGAIL ZUGER (NYT) 1657 words
Late Edition - Final , Section F , Page 1 , Column 1

http://query.nytimes.com/gst/abstract.html?res=F40B14FC3C540C748DDDA00894DA404482

ABSTRACT - Georgetown University study finds that 21 percent of 354 prescription drugs released from 1980 to 1999 had their recommended doses corrected at later date, almost always to lower dose; finds that drugs released in last five years are even more likely to have instructions changed than older ones; findings support longstanding concerns among some experts that drugs are being studied at excessively high doses to emphasize their effects and marketed at same high doses to maximize profits;  . . .Twenty percent of prescription drugs are marketed with instructions for use that must later be corrected by the manufacturer, researchers say -- almost always to lower the recommended dose or to warn that the drug may be hazardous to certain patients.

    

Drugs released in the last five years are even more likely to have their instructions changed than older ones.